%ما هو (من)٪ 1 - تعريف
QUALITY OF BEING TOXIC TO CELLS
Cytotoxic; Cytotoxin; Cytotoxins; Cytotoxicity tests, immunologic; Cytoxicity; Cytotoxicity, immunologic; Cytotoxic agent; Cytotoxia; Cytotoxic agents; Cytotoxic effects
Antibody-dependent cellular cytotoxicity
CYTOLYSIS OF TARGET CELLS BY NATURAL KILLER CELLS, EOSINOPHILS, NEUTROPHILS, MONOCYTES, OR MACROPHAGES FOLLOWING ENGAGEMENT OF ANTIBODIES BOUND TO THE TARGET CELLS
Antibody-dependent cell-mediated cytotoxicity; Antibody-Dependent Cell-Mediated Cytotoxicity; Antibody Dependent Cell Mediated Cytotoxicity; Antibody-Dependent Cellular Cytotoxicity; Antibody-dependent cell cytotoxicity; Antibody-dependent cell-mediated cytoxicity; Antibody-dependent cellular toxicity
Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system actively lyses a target cell, whose membrane-surface antigens have been bound by specific antibodies. It is one of the mechanisms through which antibodies, as part of the humoral immune response, can act to limit and contain infection.
Humanize
![chimeric]] (top right), humanized (bottom left) and chimeric/humanized (bottom middle) monoclonal antibodies. Human parts are shown in brown, non-human parts in blue.](https://commons.wikimedia.org/wiki/Special:FilePath/Chimeric and humanized antibodies.svg?width=200 "chimeric]] (top right), humanized (bottom left) and chimeric/humanized (bottom middle) monoclonal antibodies. Human parts are shown in brown, non-human parts in blue.")
ANTIBODIES FROM NON-HUMAN SPECIES WITH PROTEIN SEQUENCES MODIFIED TO MAKE THEM NEARLY IDENTICAL WITH HUMAN ANTIBODIES
Humanised antibody; Humanized monoclonal antibody; Humanize; Humanized; Humanized antibodies
·vt To give a human character or expression to.
II. Humanize ·vi To become or be made more humane; to become civilized; to be ameliorated.
III. Humanize ·vt To convert into something human or belonging to man; as, to humanize vaccine lymph.
IV. Humanize ·vt To render human or humane; to Soften; to make gentle by overcoming cruel dispositions and rude habits; to refine or civilize.
humanize
ANTIBODIES FROM NON-HUMAN SPECIES WITH PROTEIN SEQUENCES MODIFIED TO MAKE THEM NEARLY IDENTICAL WITH HUMAN ANTIBODIES
Humanised antibody; Humanized monoclonal antibody; Humanize; Humanized; Humanized antibodies
v. a.
1.
Soften, make humane.
2.
Civilize, cultivate, refine, polish, improve, enlighten, educate, reclaim from barbarism, fill with sensibility to justice, truth, and beauty.
ويكيبيديا
Cytotoxicity
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (Bitis arietans) or brown recluse spider (Loxosceles reclusa).
